PC12cells相关论文
目的:研究黄芩素对Aβn 25-35损伤PC12细胞中谷氨酸受体相关蛋白表达的影响。n 方法:将PC12细胞按随机数字表法分为对照......
Biocompatible chitosan/polyethylene glycol/multi-walled carbon nanotube composite scaffolds for neur
Carbon nanotube (CNT) composite materials are very attractive for use in neural tissue engineering and biosensor coating......
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Neuroprotective effects of chlorogenic acid against oxidative stress in PC12 cells induced by low le
Chlorogenic acid as antioxidtion,exists in edible and medicinal plants widely cultivated and consumed in the world.In do......
Etidronate and trisphosphonates are new potential candidates for neuroprotective drugs for Alzheimer
Objective Bisphosphonates(BP)is a category of drugs that are used to treat various bone diseases,such as osteoporosis,Pa......
The transcription factor nuclear factor erythroid-2-related factor 2(Nrf2)and its target heme oxygenase-1(HO-1)play crit......
7,8-Dihydroxyflavone Protects PC12 Cells against 6-Hydroxyl Dopamine-induced Cytotoxicity through Nr
Introduction: Our previous study found that 7,8-dihydroxyflavone(7,8-DHF),a new selective TrkB agonist,could protect aga......
Neuroprotective effects of plant extracts against the neurotoxicity induced by rotenone, a mitochond
Aim: Rotenone, an inhibitor of mitochondnal complex Ⅰ, has been widely regarded as a neurotoxin because it induces a Pa......
Neuroprotective effects of paeoniflorin and albiflorin, two major constituents of JD-30, on Aβ25-35-
Aim: JD-30 is an active fraction extracted from Danggui-Shaoyao-San under guidance of bioactive evaluation in our previo......
OBJECTIVE To investigate the protective effects of Naodesheng Effective Composite (NEC) on PC12 cells apoptosis induced ......
Baicalein causes alternation in dopamine metabolism in PC12 cells by inhibiting the expression of CO
Aim Baicalein is the major flavonoid obtained from the Scutellaria root.Our previous studies have demonstrated that baic......
5-Lipoxygenase (5-LOX) is the key enzyme metabolizing arachidonic acid to produce pro-inflammatory leukotrienes.The init......
The effect of hydrogen suifide on PC12 cell injury induced by the higher concentration of extrcellul
ATP is currently regarded as the cell death factor not only the energy.We have found previously that hydrogen sulphide (......
AIM To investigate protect effect of Fufangdengzhanhua dripping pill (FDD)s oxidative stress induced by hydrogen peroxid......
Protective effects and mechanisms of Catalpol and puerarin freeze-dried powder for injection on CoCl
Objective: To investigate the protective effects and mechanism of Catalpol and puerarin freeze-dried powder for injectio......
The neuroprotective effects of torularhodin against oxidative injury and apoptosis in PC12 cells,as well as the mechanis......
Aim: Oxygen-glucose deprivation/reoxygenation (OGD) is an in vitro model for cerebral ischemia-reperfusion injury, which......
Background: In both humans and animals, microwave exposures are suspected to affect cognitive functions, and various neu......
Background: Microwave radiation could change the activity, numbers, gene and protein expression of NMDAR 2B (NR2B), whic......
Normal intracellular cholesterol levels are responsible for maintaining the activation of insulin/in
Alzheimers disease (AD) is associated with abnormal cholesterol metabolism.Recent studies have suggested that AD is a ne......
Inhibitory effect of caffeic acid on activation of 5-1ipoxygenase induced by oxidative stress in PCI
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Protective effects and possible mechanisms of anti-neuronal apoptosis of Xanthoceraside on PC12 cell
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Neuroprotective Effects of Dexmedetomidine Preconditioning on Oxygen-glucose Deprivation-reoxygenati
Dexmedetomidine(DEX),a potent and highly selective agonist for α2-adrenergic receptors(α2AR),exerts neuroprotective ef......
Lead(Pb)neurotoxicity has received renewed interest with the growing evidence that Pb contributes to Alzheimers dise......
Endoplasmic reticulum chaperone GRP78 is involved in autophagy activation induced by ischemic precon
Background: Our previous finding showed that brain ischemic preconditioning mediates neuroprotection through endopla......
Objective: Autophagy serves as a stress response and it is a process involved in neurodegeneration diseases. Increas......
Vitamin E protects PC12 cells against manganese-induced cytotoxicitythe role of oxidative stress and
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Autophagy has been shown to have a protective effect against brain damage. Ligustilide (LIG) is a bioactive substance is......
Xiaoyaosan-containing serum inhibits corticosterone-induced apoptosis in PC12 cells by downregulatin
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Neuroprotective effect of Eleutheroside B on 1-methyl-4-phenylpyridinium ion-induced apoptosis in PC
Apoptosis and viability of PC12 cells following 1-methyl-4-phenylpyridinium ion (MPP+)-induced injury were monitored by ......
Protective effects of components of the Chinese herb grassleaf sweetlfag rhizome on PC12 cells incub
The major ingredients of grassleaf sweetlfag rhizome areβ-asarone and eugenol, which can cross the blood-brain barrier ......
Protective Effects of Procyanidins on 6-OHDA-induced PC12 Cells Injury and its Mechanism Exploration
Objective:To investigate the protective effect of procyanidins(PC)on PC12 cells injured induced by 6-hydroxydopamine(6-O......
目的观察不同剂量亚砷酸钠(NaAsO2)对PC12细胞(具有神经元特性的大鼠嗜铬瘤细胞)色素上皮衍生因子(PEDF)和凋亡相关因子mRNA表达的影响。......
目的 探讨富含γ-氨基丁酸(γ-aminobutyric acid,GABA)的米糠提取物(rice bran extracts,RBE)对Aβ_(25-35)致PC12细胞损伤的影响。方法......
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目的 研究H2O2诱导的PC12细胞氧化应激损伤中,能量限制(CR)及SIRT3参与的调控效应.方法 实验分4组:H2O2组,H2O2+CR组,CR组和正常对......
目的:探讨不同浓度β-淀粉样蛋白(Aβ(1-42))激活的星形胶质细胞条件培养液(ACM)对PC12细胞存活率及脑源性神经营养因子(BDNF)、乙酰胆碱酯......
目的分析川芎嗪预处理大鼠肾上腺嗜铬细胞瘤细胞株PC12细胞后过氧化氢诱导的细胞凋亡情况,探讨川芎嗪抑制脑缺血损伤中氧自由基损......
利用MaCN及缺糖引起的PC12细胞的损伤模型,研究了银杏内酯(ginkgolides)对神经细胞损伤的保护作用。结果表明,该药物对PC12细胞损伤有显著的改善作用并能显著降......